Mechanism of fatal air embolism after gastrointestinal endoscopy

Katzgraber,F.; Glenewinkel,F.; Fischler,S.; Rittner,C.; Although venous air embolism is a known complication in medical practice in general, only a single case of upper gastrointestinal endoscopy complicated by venous air embolism with consecutive acute cardiovascular failure has so far been described in literature. Here we show that gastroscopy may be accompanied by massive, i.e. fatal venous air embolism. If a vessel in the gastrointestinal tract is exposed but does not collapse (in the case of a gastric ulcer, for example) air insufflated under pressure by the gastroscope may lead to a fatal air embolism. [Read More]

Metal pins fired from unmodified blank cartridge guns and very small calibre weapons--technical and wound ballistic aspects

Rabl,W.; Riepert,T.; Steinlechner,M.; Blank cartridge guns are generally regarded as being harmless and are not considered to be firearms in most countries. A comparison of the legal situations in Germany and Austria concerning weapons is given. There have been several reports of serious injuries and even fatalities due to these weapons. Ballistic experiments show that even unmodified blank cartridge guns and very small calibre weapons can fire wire nails and can inflict potentially fatal injuries even at distances of 50 cm. [Read More]

Molecular characterization of the human protein kinase C theta gene locus (PRKCQ)

Kofler,K.; Köchl,S.; Parson,W.; Erdel,M.; Utermann,G.; Baier,G.; Members of the protein kinase C (PKC) family of serine/threonine kinases, in particular PKCtheta, play critical roles in the regulation of differentiation and proliferation of T lymphocytes. In this study the genomic structure of the human PRKCQ gene that encodes PKCtheta was determined. Two genomic P1 clones were isolated from human P1 libraries using the PKCtheta cDNA as a probe and have been used to confirm the assignment of the single PRKCQ locus to chromosome 10p15 by FISH analysis. [Read More]