Postmortem neopterin concentrations: comparison of diagnoses with and without cellular immunological background

Ambach,E.; Tributsch,W.; Rabl,W.; Fuchs,D.; Reibnegger,G.; Henn,R.; Wachter,H.; Increased neopterin levels in urine and serum of living humans indicate an activation of the cellular immune system. We investigated 119 urine and 48 serum samples from 129 corpses taken at necropsy; 29 cases with a background of cellular immune activation were compared to 100 corpses with no such indication. Our investigations show the feasibility of postmortem neopterin measurements. However, different kinetics of serum and urine concentrations after death were observed. [Read More]