Parson,W.; Eduardoff,M.; Xavier,C.; Bertoglio,B.; Teschler-Nicola,M.; In 1976 human remains of seven individuals were discovered in a storage pit located within the Late Bronze Age (9(th) century B.C.) settlement Stillfried an der March, Austria. In contrast to the common funeral rite of cremation typical for the Urnfield culture (1300-800 B.C.) the individuals’ skeletal remains were found outstandingly preserved (Figure S1). As a result, the burial was subject to various investigations, including two conflicting genealogical pedigree reconstructions, one of which was favoured by later geological fingerprinting. [Read More]

Weber,A.; Klocker,H.; Oberacher,H.; Gnaiger,E.; Neuwirt,H.; Sampson,N.; Eder,I.E.; The idea of using metabolic aberrations as targets for diagnosis or therapeutic intervention has recently gained increasing interest. In a previous study, our group discovered intriguing differences in the oxidative mitochondrial respiration capacity of benign and prostate cancer (PCa) cells. In particular, we found that PCa cells had a higher total respiratory activity than benign cells. Moreover, PCa cells showed a substantial shift towards succinate-supported mitochondrial respiration compared to benign cells, indicating a re-programming of respiratory control. [Read More]

Müller,P.; Alonso,A.; Barrio,P.A.; Berger,B.; Bodner,M.; Martin,P.; Parson,W.; DnaseqexConsortium;

Forensic Sci Int Genet 2018 36:95-103
PubMed: 29986231

Larmuseau,M.H.D.; Bodner,M.; The discovery of the presumably lost grave of the controversial English king Richard III in Leicester (U.K.) was one of the most important archaeological achievements of the last decennium. The skeleton was identified beyond reasonable doubt, mainly by the match of mitochondrial DNA to that of living maternal relatives, along with the specific archaeological context. Since the genetic genealogical analysis only involved the DNA sequences of a single 15th century individual and a few reference persons, biologists might consider this investigation a mere curiosity. [Read More]

Phillips,C.; Gettings,K.B.; King,J.L.; Ballard,D.; Bodner,M.; Borsuk,L.; Parson,W.; The STR sequence template file published in 2016 as part of the considerations from the DNA Commission of the International Society for Forensic Genetics on minimal STR sequence nomenclature requirements, has been comprehensively revised and audited using the latest GRCh38 genome assembly. The list of forensic STRs characterized was expanded by including supplementary autosomal, X- and Y-chromosome microsatellites in less common use for routine DNA profiling, but some likely to be adopted in future massively parallel sequencing (MPS) STR panels. [Read More]