Kaloudi-Chantzea,A.; Martinou,E.; Seintis,K.; Karakostas,N.; Giastas,P.; Pitterl,F.; Oberacher,H.; Fakis,M.; Pistolis,G.;

We present here the self-assembly of a green-emitting metallosupramolecular rhomboid into a rigid, highly-ordered 3D multichromophoric network through the mediation of a tetra-anionic violet-blue molecular emitter. Control was obtained on the spatial topology, the electronic energy landscape and the fluorescence polarization of the interacting dipoles.

Chem Commun (Camb) 2016 52:3388-91
PubMed: 26879596

Desmyter,S.; Bodner,M.; Huber,G.; Dognaux,S.; Berger,C.; Noel,F.; Parson,W.; Hairs from the same donor have been found to differ in mtDNA sequence within and among themselves and from other tissues, which impacts interpretation of results obtained in a forensic setting. However, little is known on the magnitude of this phenomenon and published data on systematic studies are scarce. We addressed this issue by generating mtDNA control region (CR) profiles of >450 hair fragments from 21 donors by Sanger-type sequencing (STS). [Read More]

Chaitanya,L.; vanOven,M.; Brauer,S.; Zimmermann,B.; Huber,G.; Xavier,C.; Parson,W.; deKnijff,P.; Kayser,M.; The use of mitochondrial DNA (mtDNA) for maternal lineage identification often marks the last resort when investigating forensic and missing-person cases involving highly degraded biological materials. As with all comparative DNA testing, a match between evidence and reference sample requires a statistical interpretation, for which high-quality mtDNA population frequency data are crucial. Here, we determined, under high quality standards, the complete mtDNA control-region sequences of 680 individuals from across the Netherlands sampled at 54 sites, covering the entire country with 10 geographic sub-regions. [Read More]

Eduardoff,M.; Gross,T.E.; Santos,C.; delaPuente,M.; Ballard,D.; Strobl,C.; Borsting,C.; Morling,N.; Fusco,L.; Hussing,C.; Egyed,B.; Souto,L.; Uacyisrael,J.; SyndercombeCourt,D.; Carracedo,A.; Lareu,M.V.; Schneider,P.M.; Parson,W.; Phillips,C.; E.UROFORGEN-NoEConsortium; Parson,W.; Phillips,C.; The EUROFORGEN Global ancestry-informative SNP (AIM-SNPs) panel is a forensic multiplex of 128 markers designed to differentiate an individual’s ancestry from amongst the five continental population groups of Africa, Europe, East Asia, Native America, and Oceania. A custom multiplex of AmpliSeq PCR primers was designed for the Global AIM-SNPs to perform massively parallel sequencing using the Ion PGM system. [Read More]

Pham,HaiT.; Arnhard,Kathrin; Asad,YasminJ.; Deng,Lu; Felder,ThomasK.; St.John-Williams,Lisa; Kaever,Volkhard; Leadley,Michael; Mitro,Nico; Muccio,Stephane; Prehn,Cornelia; Rauh,Manfred; Rolle-Kampczyk,Ulrike; Thompson,J.Will; Uhl,Olaf; Ulaszewska,Maria; Vogeser,Michael; Wishart,DavidS.; Koal,Therese; Background: The increasing relevance of individual bile acids quantification in biological samples requires analytical standardization to guarantee robustness and reliability of laboratory results. We have organized the first international ring trial, carried out in 12 laboratories, to evaluate the newly developed LC-MS/MS–based test kit for bile acid analysis.Methods: Each laboratory received a Biocrates® Bile Acids Kit including system suitability test (SST) protocol. [Read More]