GHEP-ISFG proficiency test 2011: Paper challenge on evaluation of mitochondrial DNA results

Prieto,L.; Alves,C.; Zimmermann,B.; Tagliabracci,A.; Prieto,V.; Montesino,M.; Whittle,M.R.; Anjos,M.J.; Cardoso,S.; Heinrichs,B.; Hernandez,A.; Lopez-Parra,A.M.; Sala,A.; Saragoni,V.G.; Burgos,G.; Marino,M.; Paredes,M.; Mora-Torres,C.A.; Angulo,R.; Chemale,G.; Vullo,C.; Sanchez-Simon,M.; Comas,D.; Puente,J.; Lopez-Cubria,C.M.; Modesti,N.; Aler,M.; Merigioli,S.; Betancor,E.; Pedrosa,S.; Plaza,G.; Masciovecchio,M.V.; Schneider,P.M.; Parson,W.; The GHEP-ISFG Working Group performed a collaborative exercise to monitor the current practice of mitochondrial (mt)DNA reporting. The participating laboratories were invited to evaluate a hypothetical case example and assess the statistical significance of a match between the haplotypes of a case (hair) sample and a suspect. [Read More]

High resolution mapping of Y haplogroup G in Tyrol (Austria)

Berger,B.; Niederstätter,H.; Erhart,D.; Gassner,C.; Schennach,H.; Parson,W.; The distribution of Y-chromosomal haplogroup G2a (G-P15) in present-day paternal lineages in Tyrol (Austria) was analyzed by applying a high-density regional sampling scheme that also covered remote mountain areas. There is evidence from ancient genetic data for a high frequency of Y-chromosomal haplogroup G in prehistoric populations of Central Europe, whilst nowadays levels well below 10% are routinely observed. A population sample comprising approximately 3700 specimens was analyzed for Y-chromosomal variation by genotyping Y-SNPs and Y-STRs. [Read More]