Psychosocial state after bariatric surgery is associated with the serotonin-transporter promoter polymorphism

 Published in 2013

Defrancesco,M.; Liebaert,J.; Kemmler,G.; Aigner,F.; Niederstätter,H.; Parson,W.; Kinzl,J.F.; BACKGROUND: Bariatric surgery is the method of choice in the treatment of morbid obesity. Different genotypes of the serotonin transporter gene (5-HTT) are known to impact the prevalence of psychiatric disorders and the psychosocial state in obese individuals. In this study, we examined the influence of the 5-HTTLPR polymorphism on physiologic and psychosocial measures in morbidly obese women after bariatric surgery. METHODS: We investigated women 1-5 years after bariatric surgery using a semi-structured interview and the Beck Depression Inventory, the Moorhead-Ardelt Quality of life questionnaire, the NEO-Five Factor Inventory and a Resilience scale. [Read More]

RNA/DNA co-analysis from human saliva and semen stains - Results of a third collaborative EDNAP exercise

 Published in 2013

Haas,C.; Hanson,E.; Anjos,M.J.; Banemann,R.; Berti,A.; Borges,E.; Carracedo,A.; Carvalho,M.; Courts,C.; De,Cock G.; Dotsch,M.; Flynn,S.; Gomes,I.; Hollard,C.; Hjort,B.; Hoff-Olsen,P.; Hribikova,K.; Lindenbergh,A.; Ludes,B.; Maronas,O.; McCallum,N.; Moore,D.; Morling,N.; Niederstätter,H.; Noel,F.; Parson,W.; Popielarz,C.; Rapone,C.; Roeder,A.D.; Ruiz,Y.; Sauer,E.; Schneider,P.M.; Sijen,T.; Court DS; Sviezena,B.; Turanska,M.; Vidaki,A.; Zatkalikova,L.; Ballantyne,J.; A third collaborative exercise on RNA/DNA co-analysis for body fluid identification and STR profiling was organized by the European DNA Profiling Group (EDNAP). Twenty saliva and semen stains, four dilution series (10-0. [Read More]

Serotonin transporter genotype (5-HTTLPR) and electrocortical responses indicating the sensitivity to negative emotional cues

 Published in 2013

Papousek,I.; Reiser,E.M.; Schulter,G.; Fink,A.; Holmes,E.A.; Niederstätter,H.; Nagl,S.; Parson,W.; Weiss,E.M.; Growing literature indicates that emotional reactivity and regulation are strongly linked to genetic modulation of serotonergic neurotransmission. However, until now, most studies have focused on the relationship between genotypic markers, in particular the serotonin transporter-linked polymorphic region (5-HTTLPR), and neural structures using MRI. The current study aimed to bridge the gap between the relevant MRI literature on the effects of the 5-HTTLPR genotype and the research tradition focusing on transient lateralized changes of electrocortical activity in the prefrontal cortex using electroencephalography (EEG). [Read More]

Simultaneous quantification of verbenalin and verbascoside in Verbena officinalis by ATR-IR and NIR spectroscopy

 Published in 2013

Schönbichler,S.A.; Bittner,L.K.; Pallua,J.D.; Popp,M.; Abel,G.; Bonn,G.K.; Huck,C.W.; Attenuated-total-reflectance infrared spectroscopy (ATR-IR) and near-infrared diffuse reflectance spectroscopy (NIR) in hyphenation with multivariate analysis was utilized to quantify verbenalin and verbascoside in Verbena officinalis. A new high performance liquid chromatography (HPLC) method as a reference was established and validated. For both vibrational spectroscopic methods test-set and cross validation were performed. Different data-pre-treatments like SNV, 1st and 2nd derivative were applied to remove systematic errors and were evaluated. [Read More]