Frequency data for 17 Y-chromosomal STRs and 19 Y-chromosomal SNPs in the Tyrolean district of Reutte, Austria

Erhart,D.; Berger,B.; Niederstätter,H.; Gassner,C.; Schennach,H.; Parson,W.; We established a data set of 17 Y-STRs of 261 males from the Tyrolean district of Reutte. In total we observed 228 different haplotypes, 203 of which were unique and 25 occurred between two and four times. The haplotype diversity was 0.9987 and the discrimination capacity was 0.8736. Further, samples were typed with a selection of 19 Y-SNPs to establish the haplogroup background. Data are available in the Y chromosome haplotype reference database under accession number YA003715 [Read More]

Germline mutations of STR-alleles include multi-step mutations as defined by sequencing of repeat and flanking regions

Dauber,E.M.; Kratzer,A.; Neuhuber,F.; Parson,W.; Klintschar,M.; Bar,W.; Mayr,W.R.; Well defined estimates of mutation rates are a prerequisite for the use of short tandem repeat (STR-) loci in relationship testing. We investigated 65 isolated genetic inconsistencies, which were observed within 50,796 allelic transfers at 23 STR-loci (ACTBP2 (SE33), CD4, CSF1PO, F13A1, F13B, FES, FGA, vWA, TH01, TPOX, D2S1338, D3S1358, D5S818, D7S820, D8S1132, D8S1179, D12S391, D13S317, D16S539, D17S976, D18S51, D19S433, D21S11) in Caucasoid families residing in Austria and Switzerland. [Read More]

In situ labeling of DNA reveals interindividual variation in nuclear DNA breakdown in hair and may be useful to predict success of forensic genotyping of hair

Szabo,S.; Jaeger,K.; Fischer,H.; Tschachler,E.; Parson,W.; Eckhart,L.; Hair fibers are formed by keratinocytes of the hair follicle in a process that involves the breakdown of the nucleus including DNA. Accordingly, DNA can be isolated with high yield from the hair bulb which contains living keratinocytes, whereas it is difficult to prepare from the distal portions of hair fibers and from shed hair. Nevertheless, forensic investigations are successful in a fraction of shed hair samples found at crime scenes. [Read More]

Mitochondrial DNA control region data from indigenous Angolan Khoe-San lineages

Fendt,L.; Huber,G.; Rock,A.W.; Zimmermann,B.; Bodner,M.; Delport,R.; Schmidt,K.; Parson,W.; Here we provide 129 complete mitochondrial control region sequences of indigenous Khoe-San individuals from Angola to contribute to the still underrepresented pool of data from Africa. The dataset consists of exclusively African lineages with a majority of Sub-Saharan haplogroups. The probability of a random match was calculated as 0.09. The data set comprises 21 haplotypes occurring more than once and 17 unique haplotypes. [Read More]

MtDNA diversity of Ghana: a forensic and phylogeographic view

Fendt,L.; Röck,A.; Zimmermann,B.; Bodner,M.; Thye,T.; Tschentscher,F.; Owusu-Dabo,E.; Graziosi,G.; Schneider,P.M.; Parson,W.; West Africa is characterized by a migration history spanning more than 150,000 years. Climate changes but also political circumstances were responsible for several early but also recent population movements that shaped the West African mitochondrial landscape. The aim of the study was to establish a Ghanaian mtDNA dataset for forensic purposes and to investigate the diversity of the Ghanaian population sample with respect to surrounding populations. [Read More]