Holland,M.M.; Parson,W.; GeneMarker((R)) HID was assessed as a software tool for the analysis of forensic short tandem repeat (STR) data and as a resource for analysis of custom STR multiplexes. The software is easy to learn and use, and includes design features that have the potential to reduce user fatigue. To illustrate reliability and accuracy, STR data from both single-source and mixture profiles were analyzed and compared to profiles interpreted with another software package. [Read More]

Baubin,M.; Rabl,W.;

Resuscitation 2011
PubMed: 21819952

Herndler-Brandstetter,D.; Landgraf,K.; Jenewein,B.; Tzankov,A.; Brunauer,R.; Brunner,S.; Parson,W.; Kloss,F.; Gassner,R.; Lepperdinger,G.; Grubeck-Loebenstein,B.; Recently, a key role in memory T cell homing and survival has been attributed to the bone marrow (BM) in mice. In the human BM, the repertoire, function, and survival niches of CD4(+) and CD8(+) T cells have not yet been elucidated. In this study, we demonstrate that CD4(+) and CD8(+) effector memory T cells accumulate in the human BM and are in a heightened activation state as revealed by CD69 expression. [Read More]

Schubert,B.; Oberacher,H.; In this study the impact of solvent conditions on the performance of muLC/MS for the analysis of basic drugs was investigated. Our aim was to find experimental conditions that enable high-performance chromatographic separation particularly at overloading conditions paired with a minimal loss of mass spectrometric detection sensitivity. A focus was put on the evaluation of the usability of different kinds of acidic modifiers (acetic acid (HOAc), formic acid (FA), methansulfonic acid (CH(3)SO(3)H), trifluoroacetic acid (TFA), pentafluoropropionic acid (PFPA), and heptafluorobutyric acid (HFBA)). [Read More]

Defrancesco,M.; Niederstätter,H.; Parson,W.; Oberacher,H.; Hinterhuber,H.; Canazei,M.; Bidner,J.; Deisenhammer,E.A.; Kemmler,G.; Weiss,E.M.; Marksteiner,J.; Monoamines, such as serotonin, dopamine, and norepinephrine, play a crucial role in the regulation of emotion processing and mood. In this study, we investigated how polymorphisms of the serotonin transporter (5-HTT) and catechol-O-methyltransferase (COMT) influence emotion recognition abilities. We recruited 88 female undergraduate students and assessed 5-HTT genotype and the COMT Val158Met polymorphism. The subjects completed two computerized tasks: The Penn Emotion Recognition Test (ER40) and the Penn Emotion Acuity Test (PEAT). [Read More]