Röck,A.; Irwin,J.; Dür,A.; Parsons,T.; Parson,W.; The analysis of the haploid mitochondrial (mt) genome has numerous applications in forensic and population genetics, as well as in disease studies. Although mtDNA haplotypes are usually determined by sequencing, they are rarely reported as a nucleotide string. Traditionally they are presented in a difference-coded position-based format relative to the corrected version of the first sequenced mtDNA. This convention requires recommendations for standardized sequence alignment that is known to vary between scientific disciplines, even between laboratories. [Read More]

Pesta,D.; Hoppel,F.; Macek,C.; Messner,H.; Faulhaber,M.; Kobel,C.; Parson,W.; Burtscher,M.; Schocke,M.; Gnaiger,E.; Endurance and strength training are established as distinct exercise modalities, increasing either mitochondrial density or myofibrillar units. Recent research, however, suggests that mitochondrial biogenesis is stimulated by both training modalities. To test the training “specificity” hypothesis, mitochondrial respiration was studied in permeabilized muscle fibers from 25 sedentary adults after endurance (ET) or strength training (ST) in normoxia or hypoxia [fraction of inspired oxygen (Fi(O(2))) = 21% or 13. [Read More]

Bodner,M.; Zimmermann,B.; Röck,A.; Kloss-Brandstätter,A.; Horst,D.; Horst,B.; Sengchanh,S.; Sanguansermsri,T.; Horst,J.; Kramer,T.; Schneider,P.M.; Parson,W.; BACKGROUND: Vast migrations and subsequent assimilation processes have shaped the genetic composition of Southeast Asia, an area of close contact between several major ethnic groups. To better characterize the genetic variation of this region, we analyzed the entire mtDNA control region of 214 unrelated donors from Laos according to highest forensic quality standards. To detail the phylogeny, we inspected selected SNPs from the mtDNA coding region. [Read More]

Oberacher,H.; Pitterl,F.;

Int J.Immunopathol.Pharmacol. 2011 304:124-129

Roewer,L.; Parson,W.;

Forensic Sci.Int Genet. 2011
PubMed: 21397887