A study concerning the blood/breath alcohol conversion factor Q: concentration dependency and its applicability in daily routine

Pavlic,M.; Grubwieser,P.; Brandstätter,A.; Libiseller,K.; Rabl,W.; The conversion factor Q, obtained by division of blood alcohol concentration (BAC) by breath alcohol concentration (BrAC) is a widely discussed topic due to its great variance. By Austrian law, regulations frequently require an estimation of a corresponding BAC by a measured BrAC. It is known that Q depends among other things, on the alcohol kinetic state of the person being tested, which mathematically can be transformed to a dependency on the BrAC. [Read More]

AAK und â60

Pavlic,M.; Grubwieser,P.; Libiseller,K.; Rabl,W.;

Rechtsmedizin 2006

Accurate determination of allelic frequencies in mitochondrial DNA mixtures by electrospray ionization time-of-flight mass spectrometry

Oberacher,H.; Niederstätter,H.; Huber,C.G.; Parson,W.; The mitochondrial locus 16519T/C was used as a model for the evaluation of the benefits of ion-pair reversed-phase high-performance liquid chromatography on-line hyphenated to electrospray ionization time-of-flight mass spectrometry (ICEMS assay) for the determination of allelic frequencies of single nucleotide polymorphisms. This marker has gained interest in forensic science owing to its ability to increase the discrimination power of mitochondrial DNA testing as a consequence of its high variability across various populations. [Read More]

Analysis of artificially degraded DNA using STRs and SNPs - results of a collaborative European (EDNAP) exercise

Dixon,L.A.; Dobbins,A.E.; Pulker,H.K.; Butler,J.M.; Vallone,P.M.; Coble,M.D.; Parson,W.; Berger,B.; Grubwieser,P.; Mogensen,H.S.; Morling,N.; Nielsen,K.; Sanchez,J.J.; Petkovski,E.; Carracedo,A.; Sanchez-Diz,P.; Ramos-Luis,E.; Brion,M.; Irwin,J.A.; Just,R.S.; Loreille,O.; Parsons,T.J.; Syndercombe-Court; Schmitter,H.; Stradmann-Bellinghausen,B.; Bender,K.; Gill,P.; Recently, there has been much debate about what kinds of genetic markers should be implemented as new core loci that constitute national DNA databases. The choices lie between conventional STRs, ranging in size from 100 to 450 bp; mini-STRs, with amplicon sizes less than 200 bp; and single nucleotide polymorphisms (SNPs). [Read More]