Klestil,T.; Morlock,M.M.; Schwieger,K.; Sellenschloh,K.; Curda,B.; Biedermann,R.; Hennerbichler,A.; Schmoelz,W.; Rabl,W.; Blauth,M.; The aim of the present in vitro study was to evaluate migrational characteristics of cementless primary hip arthroplasty stems in combination with a diameter 50 mm head (hemiarthroplasty) and a diameter 28 mm head in and with a polyethylene cup (total hip arthroplasty) in fresh-frozen human specimens. Two different types (Endo SL, FMT) were implanted into seven pairs of fresh-frozen human femoral specimens. [Read More]

Pfister,G.; Weiskopf,D.; Lazuardi,L.; Kovaiou,R.D.; Cioca,D.P.; Keller,M.; Lorbeg,B.; Parson,W.; Grubeck-Loebenstein,B.; One of the most striking changes in the primary lymphoid organs during human aging is the progressive involution of the thymus. As a consequence, the rate of naive T cell output dramatically declines with age and the peripheral T cell pool shrinks. These changes lead to increased incidence of severe infections and decreased protective effect of vaccinations in the elderly. Little is, however, known of the composition and function of the residual naive T cell repertoire in elderly persons. [Read More]

Pavlic,M.; Libiseller,K.; Grubwieser,P.; Rabl,W.;

Rechtsmedizin 2006

Bravi,C.M.; Parson,W.; Bandelt,H.J.;

• 2006*

Oberacher,H.; Niederstätter,H.; Pitterl,F.; Parson,W.; We present a rapid and informative mitochondrial DNA profiling system, which has high forensic impact. The assay is based on the analysis of a 23-plex PCR by ion-pair reversed-phase high-performance liquid chromatography online hyphenated to electrospray ionization time-of-flight mass spectrometry (ICEMS). In a single 25-min run, an overall number of 627 nucleotide positions were screened. The vast majority of observed sequence variations were explainable by alterations of the allelic states of the 23 target SNPs, which were selected on their ability to increase forensic discrimination within West Eurasian populations. [Read More]