Brion,M.; Dupuy,B.M.; Heinrich,M.; Hohoff,C.; Hoste,B.; Ludes,B.; Mevag,B.; Morling,N.; Niederstätter,H.; Parson,W.; Sanchez,J.; Bender,K.; Siebert,N.; Thacker,C.; Vide,C.; Carracedo,A.; A collaborative study was carried out by the European DNA Profiling Group (EDNAP) in order to evaluate the performance of Y-chromosome binary polymorphism analysis in different European laboratories. Four blood samples were sent to the laboratories, to be analysed for 11 Y-chromosome single nucleotide polymorphisms (SNPs): SRY-1532, M40, M35, M213, M9, 92R7, M17, P25, M18, M153 and M167. [Read More]

Kurzthaler,I.; Wambacher,M.; Golser,K.; Sperner,G.; Sperner-Unterweger,B.; Haidekker,A.; Pavlic,M.; Kemmler,G.; Fleischhacker,W.W.; Falls are common at all ages and especially in the elderly; it is important to understand contributing causes. Over a 1-year period we studied blood alcohol (BAC) and benzodiazepine concentrations in patients attending an emergency department because of a fall. The 22% of 615 patients tested were positive for alcohol, 55% were positive for benzodiazepines (BZD) and 1.5% were positive for both substances. [Read More]

Kurzthaler,I.; Wambacher,M.; Golser,K.; Sperner,G.; Sperner-Unterweger,B.; Haidekker,A.; Pavlic,M.; Kemmler,G.; Fleischhacker,W.W.; 1611 patients were included in this investigation. 16.7% of the patients were involved in traffic accidents, 38.2% were injured by a sudden fall, 3.5% were involved in an act of violence, 22.8% were injured by a sports related accident and 18.9% were hurt within a work-related accident. 19.5% of the patients tested positive for alcohol, 5.2% tested positive for benzodiazepines and 1. [Read More]

Hölzl,G.; Oberacher,H.; Pitsch,S.; Stutz,A.; Huber,C.G.; Ion-pair reversed-phase high-performance liquid chromatography (IP-RP-HPLC) has been evaluated as a method for the fractionation and desalting of ribonucleic acids prior to their characterization by electrospray ionization mass spectrometry. Monolithic, poly(styrene-divinylbenzene)-based capillary columns allowed the rapid and highly efficient fractionation of both synthetic and biological ribonucleic acids. The common problem of gas-phase cation adduction that is particularly prevalent in the mass spectrometric analysis of ribonucleic acids was tackled through a combination of chromatographic purification and the addition of ethylenediaminetetraacetic acid to the sample at a concentration of 25 mmol/L shortly before on-line analysis. [Read More]

Pavlic,M.; Grubwieser,P.;

• 2005*