High-throughput sequencing of forensic STRs and SNPs using the MiSeq benchtop sequencer

Xavier,C.; Parson,W.

Next Generation Sequencing (NGS) has been increasing its applications in forensic genetics in the last couple of years. Such methods bring a high multiplexing capacity and a deep sequencing resolution that put data under a new perspective. After proving its capacity with mitochondrial DNA and SNP markers, new assays comprising length polymorphisms are currently entering the market. Testing and evaluating such applications is then of utmost importance for validation and possible integration into routine casework laboratories.