Systematic Evaluation of Massively Parallel STR Sequencing in the DNASeqEx Project

Müller,P.; Berger,B.; Bodner,M.; Alonso,A.; Barrio,P.; Martin,P.; Köcher,S.; Roewer,L.; Willuweit,S.; Budowle,B.; DNASEQEX Consortium; Parson,W.

The EU funded DNASeqEx (DNA-STR Massive Sequencing & International Information Exchange) project evaluates current massively parallel sequencing (MPS) technologies in a collaborative manner. The aim of the project is to perform interlaboratory evaluation and comparison of forensically relevant parameters, such as allele calling, sensitivity, reproducibility, and concordance in STR analysis using single source and mixture samples.