Canine DNA profiling in forensic casework

 Published in 2009

Canine DNA profiling in forensic casework - joining efforts for standardization

Berger,C.; Berger,B.; Hellmann,A.; Schleenbecker,U.; Rohleder,U.; Hecht,W.; Parson,W.

Short Tandem Repeat (STR) analyses of canine cells have been applied successfully in a number of forensic cases and recently efforts were made for applying well characterized STR markers for forensic analyses. But the existence of great inter-laboratory variability indicates that the canine forensic field stil faces the urgent need for standardization and harmonization. In particular, the nature and selection of DNA markers need to be evaluated and allelic ladders as well as reference materials should be available to enable interlaboratory comparisons. Additionally a generally compatible allele nomenclature and an agreement on standardized statistical calculation methods adopted for the specific genetic characteristics of dog populations need thorough considerations.

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Small human hepatocytes in der Behandlung von Alkoholkranken?

 Published in 2007

Small human hepatocytes in der Behandlung von Alkoholkranken? Verstoffwechslung von Ethanol, Diazepam und Oxazepam in der Rotationszellkultur

Pavlic,M.; Libiseller,K.; Hermann,M.; Hengster,P.; Margreiter,R.; Wurm,M.

Über 50% der Todesfälle an Leberzirrhose sind alkoholbedingt. Einzige Therapie eines akuten Leberversagens ist nach wie vor die Transplantation – Problem der Organverfügbarkeit.

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AAK und β60

 Published in 2006

AAK und β60

Pavlic,M.; Grubwieser,P.; Libiseller,K.; Rabl,W.

In Österreich sind, wie in vielen europäischen Ländern, Grenzwerte der Atemalkoholkonzentration (AAK) denen der Blutalkoholkonzentration (BAK) rechtlich gleichgestellt. Da in der Praxis oft zeitliche Differenzen zwischen einem Vorfall (Unfall, Anhaltung) und einer Alkoholmessung, die meist in der Atemluft durchgeführt wird, bestehen, sind Rückrechnungen auf den Vorfallszeitpunkt erforderlich.

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Another soberade on the market

 Published in 2005

Another “soberade” on the market: does OUTOX keep its promise?

Pavlic,M.; Libiseller,K.; Grubwieser,P.; Sauper,T.; Rabl,W.

A new fructose containing soft drink was put on the market, OUTOX. This drink is promoted as “soberade”, promising accelerated alcohol reducing and hangover preventing effects.

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Characterization of mtDNA SNP typing

 Published in 2005

Characterization of mtDNA SNP typing using quantitative rtPCR for forensic purposes

Niederstätter,H.; Coble,M.; Parsons,T.; Parson,W.

The major limitation of forensic mitochondrial DNA (mtDNA) typing is the low power of discrimination that is obtained when common haplotypes are present.

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